The DOx series of chemicals, also known as dimethoxy-substituted phenethylamines, part or a broad class of psychedelic amphetamines
They were first synthesized by Alexander Shulgin in the mid-to-late 1960’s.
There are many DOx chemicals, but most generally users encounter 4 common analogues:
DOB (Dimethoxybromoamphetamine)
DOC (Dimethoxychloroamphetamine)
DOI (Dimethoxyiodoamphetamine)
DOM (Dimethoxymethylamphetamine)
How are the DOx Series Chemicals Used?
The DOx analogues are found in blotter, liquid and powder form, they are almost always ingested orally.
Due to the similarities in effects and very low dosages, they have, and continue to be, substituted for or sold as LSD.
Dosage, effects, and duration vary greatly by dose. For the most common analogues the dosage is as follows:
DOB: Dose: 1 - 3 mg, Duration: 18 - 30 hrs.
DOC: Dose: 1 - 5 mg, Duration: 8 - 20 hrs.
DOI: Dose: 1.5 - 3 mg, Duration: 16 - 30 hrs.
DOM: Dose: 1 - 10 mg, Duration: 12 - 20 hrs.
What are the Effects of the DOx Series Chemicals?
The DOx chemicals, as psychedelics, produce altered conciousness, sweating, euphoria, audio and visual hallucinations, increased perception of senses, increased appreciation for music and lights, halos around lights, color amplification, a feeling of one-ness with one's self or others, but can also cause paranoia, intense fear, and high doses can cause severe vasoconstriction in the extremities.
The DOx experience is very similar to LSD, but longer lasting, and each analogue acts slightly different:
DOB: Behaves almost identically to LSD, but a come-up and plateau lasting over 3-6x longer than LSD, it also tends to be less confusing and more energetic than LSD.
DOC: Exhibits full-range visual, audio, physical, and mental effects which tend to feel very ‘clear’. Shulgin also states that DOC has an uncharacteristic sense of calm.
DOI: Has a much heavier ‘body-load’ than the other DOx analogues, and is markedly longer lasting, and can also cause the inability to sleep for multiple days after the drug has been taken.
DOM: Generally has a very clear stimulation that unlike the other DOx series chemicals, has a very subtle stimulation, commonly described as "non-excessive."
Be Careful...
DOx series chemicals are very long lasting, and also have a long come-up, users commonly re-dose thinking they didn’t take enough.
The DOx series chemicals’ effects are greatly dose-dependant, the difference of 1 mg can make an incredible difference in the feeling and duration of the ‘trip.’
In the last few decades, the DOx analogues have been accidentally and purposefully misrepresented as LSD. Upon tasting the chemical, if one notices a highly bitter or "chemically" taste, this should serve as a warning sign that the drug is not LSD, but likely a psychedelic amphetamine (DOB, DOC, DOI, DOM.) However, blotter paper may have a taste regardless of the chemical on it, due to ink or solvent used.
Misrepresentation as LSD could be potentially dangerous, as the DOx series do not have the known safety profile of LSD; Unlike LSD, the DOx series can have physically harmful (if not fatal) effects in overdose. High doses may cause serious vasoconstriction of the extremities.
This misrepresentation was most widely publicized during the 70’s and 80’s, when DOM was first introduced to the market. It was sold as STP, which is an acronym for Serenity, Tranquility, and Peace. It was not until there were multiple, highly publicized hospitalizations for overdose that the true chemical identity was made known to users.